Promoting sustainable production of fish in aquaculture: Mechanistic action of diketopiperazine Cyclo-Phe-Pro in combating oxidative stress-induced infertility in zebrafish

Promoting sustainable production of fish in aquaculture: Mechanistic action of diketopiperazine Cyclo-Phe-Pro in combating oxidative stress-induced infertility in zebrafish

 

School

School of Medical and Life Sciences

Project Description

Aquaculture and fisheries are essential for the conservation of fish stocks and the production of animal feed. The Annual Fisheries Statistics showed that fish imports are about 1.9 times greater than exports, which explains the decline in fish self-sufficiency (95.27% in 2020 to 91.74% in 2021). High-density farming, temperature variations, salinity, and chemical contaminants can all cause fish to produce free radicals. Free radicals destroy lipids, proteins, and DNA, causing physiological problems such as reproductive failure. Free radicals damage sperm membranes and impair motility, affecting fertilisation success. Oxidative stress reduces egg production and embryo development, lowering their viability. Hence, addressing oxidative stress-induced fertility is crucial to sustainable aquaculture that supplies high-value fish as a protein source. 

Vacancy For

Graduate Research Assistant

Number of Vacancies

1

Duration

2 years

Requirements

  1. Completed Bachelor degree in Biomedical Science, Molecular Biology or any related field with a minimum CGPA of 3.20
  2. For Malaysian applicants only
  3. Successful candidates will be provided a monthly allowance of RM2,000
  4. Enrollment into MSc Life Sciences (Full time) in School of Medical and Life Sciences, Sunway University