Dr Lim Hui Xuan

Dr Lim Hui Xuan

  • Lecturer
Sunway Microbiome Centre

Biography

Dr Lim Hui Xuan is Research Fellow at Centre for Virus and Vaccine Research, Sunway University. She has performed various laboratory experiments related to immune cells culture. During her postgraduate study at Korea University, she researched on the role of cytokines in cancer Immunotherapy, specifically on the differentiation and immunosuppressive activity of myeloid-derived suppressor cells. Dr Lim is currently studying the immunogenicity of mutated live-attenuated vaccines against enterovirus 71 (EV-A71).

Academic & Professional Qualifications

  • PhD in Life Science, Korea University, South Korea (2016)
  • BSc (Hons) Science, University of Malaya, Malaysia (2009)

Research Interests

  • Immunotherapy for cancer
  • Innate and adaptive immunity
  • Vaccinology
  • Viral immunology

Notable Publications

  1. Lim, H. X., Jung, H. J., Lee, A., Park, S. H., Han, B. W., Cho, D., & Kim, T. S. (2018). Lysyl-transfer RNA synthetase induces the maturation of dendritic cells through MAPK and NF-κB pathways, strongly contributing to enhanced Th1 cell responses. Journal of Immunology, 201(9), 2832–2841.
  2. Lim, H. X., Choi, S., Cho, D., & Kim, T. S. (2017). IL-33 inhibits the differentiation and immunosuppressive activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. Immunology and Cell Biology, 95(1), 99–107.
  3. Lim, H. X., Hong, H. J., Cho, D., & Kim, T. S. (2014). IL-18 enhances immunosuppressive responses by promoting differentiation into monocytic myeloid-derived suppressor cells. Journal of Immunology, 193(11), 5453–5460.
  4. Lim, H. X., Hong, H. J., Jung, M. Y., Cho, D., & Kim, T. S. (2013). Principal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18. Journal of Immunology, 63(2), 179–186.